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KBP-066A, a long-acting dual amylin and calcitonin receptor agonist, induces weight loss and improves glycemic control in obese and diabetic rats

OBJECTIVE: Dual amylin and calcitonin receptor agonists (DACRAs) are novel therapeutic agents that not only improve insulin sensitivity but also work as an adjunct to established T2DM therapies. DACRAs are currently administered once daily, though it is unknown whether DACRAs with increased plasma h...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Andreassen, K.V., Larsen, A.T., Sonne, N., Mohamed, K.E., Karsdal, M.A., Henriksen, K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313742/
https://ncbi.nlm.nih.gov/pubmed/34214708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101282
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