Structural and Functional Attributes of the Interleukin-36 Receptor

Signal transduction by the IL-36 receptor (IL-36R) is linked to several human diseases. However, the structure and function of the IL-36R is not well understood. A molecular model of the IL-36R complex was generated and a cell-based reporter assay was established to assess the signal transduction of...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Yi, Guanghui, Ybe, Joel A., Saha, Siddhartha S., Caviness, Gary, Raymond, Ernest, Ganesan, Rajkumar, Mbow, M. Lamine, Kao, C. Cheng
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974375/
https://ncbi.nlm.nih.gov/pubmed/27307043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.723064
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