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CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress

Our previous study suggested that ceramide synthase 6 (CerS6), an enzyme in sphingolipid biosynthesis, is regulated by p53: CerS6 was elevated in several cell lines in response to transient expression of p53 or in response to folate stress, which is known to activate p53. It was not clear, however,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fekry, Baharan, Jeffries, Kristen A., Esmaeilniakooshkghazi, Amin, Ogretmen, Besim, Krupenko, Sergey A., Krupenko, Natalia I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974374/
https://ncbi.nlm.nih.gov/pubmed/27302066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.716902
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