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The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity
Transient Receptor Potential Melastatin 2 (TRPM2) is a Ca(2+)-permeable cation channel essential for immunocyte activation, insulin secretion, and postischemic cell death. TRPM2 is activated by ADP ribose (ADPR) binding to its C-terminal cytosolic NUDT9-homology (NUDT9H) domain, homologous to the so...
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| 出版年: | eLife |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974056/ https://ncbi.nlm.nih.gov/pubmed/27383051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17600 |
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