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Lung Epithelial Cell–Specific Expression of Human Lysosomal Acid Lipase Ameliorates Lung Inflammation and Tumor Metastasis in Lipa(−/−) Mice
Lysosomal acid lipase (LAL), a key enzyme in the metabolic pathway of neutral lipids, has a close connection with inflammation and tumor progression. One major manifestation in LAL-deficient (Lipa(−/−)) mice is an increase of tumor growth and metastasis associated with expansion of myeloid-derived s...
Tallennettuna:
| Julkaisussa: | Am J Pathol |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Investigative Pathology
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973654/ https://ncbi.nlm.nih.gov/pubmed/27461363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.04.014 |
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