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Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis

Bone marrow mesenchymal stem cells (MSCs) are an important participant in the tumor microenvironment, in which they promote tumor growth and progression. Here we report for the first time that depletion of lysosomal acid lipase (LAL) in MSCs impairs their abilities to stimulate tumor growth and meta...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhao, Ting, Yan, Cong, Du, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308640/
https://ncbi.nlm.nih.gov/pubmed/27531897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11244
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