Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

Ferroptosis is an iron-dependent, oxidative cell death, and is distinct from apoptosis, necrosis and autophagy. In this study, we demonstrated that lysosome disrupting agent, siramesine and a tyrosine kinase inhibitor, lapatinib synergistically induced cell death and reactive oxygen species (ROS) in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ma, S, Henson, E S, Chen, Y, Gibson, S B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973350/
https://ncbi.nlm.nih.gov/pubmed/27441659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.208
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