BikDD Eliminates Breast Cancer Initiating Cells and Synergizes with Lapatinib for Breast Cancer Treatment

Breast cancer initiating cells (BCICs), which can fully recapitulate the tumor origin and are often resistant to chemo- and radiotherapy, are currently considered as a major obstacle for breast cancer treatment. Here, we show that BIKDD, a constitutively active mutant form of proapoptotic gene, BIK,...

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Detalhes bibliográficos
Main Authors: Lang, Jing-Yu, Hsu, Jennifer L., Meric-Bernstam, Funda, Chang, Chun-Ju, Wang, Qingfei, Bao, Yi, Yamaguchi, Hirohito, Xie, Xiaoming, Woodward, Wendy A., Yu, Dihua, Hortobagyi, Gabriel N., Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172580/
https://ncbi.nlm.nih.gov/pubmed/21907925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.07.017
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