BikDD Eliminates Breast Cancer Initiating Cells and Synergizes with Lapatinib for Breast Cancer Treatment

Breast cancer initiating cells (BCICs), which can fully recapitulate the tumor origin and are often resistant to chemo- and radiotherapy, are currently considered as a major obstacle for breast cancer treatment. Here, we show that BIKDD, a constitutively active mutant form of proapoptotic gene, BIK,...

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Bibliographic Details
Main Authors: Lang, Jing-Yu, Hsu, Jennifer L., Meric-Bernstam, Funda, Chang, Chun-Ju, Wang, Qingfei, Bao, Yi, Yamaguchi, Hirohito, Xie, Xiaoming, Woodward, Wendy A., Yu, Dihua, Hortobagyi, Gabriel N., Hung, Mien-Chie
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172580/
https://ncbi.nlm.nih.gov/pubmed/21907925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.07.017
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