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Die and let live: harnessing BikDD to combat breast cancer stem cells

One of the possible mechanisms contributing to the intrinsic resistance of cancer stem cells (CSCs) to conventional therapies is the inefficiency of activating the apoptotic machinery. In a recent study by Lang and colleagues, the engineered constitutively active pro-apoptotic protein BikDD, which w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Giuliano, Mario, Trivedi, Meghana V, Schiff, Rachel
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446324/
https://ncbi.nlm.nih.gov/pubmed/22621279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3125
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