Proteasome inhibition enhances the killing effect of BikDD gene therapy

BikDD, a phosphorylation-mimic mutant of pro-apoptotic protein Bik, elicits strong apoptosis in cancer cells when introduced via an expression platform termed VP16-GAL4-WPRE integrated systemic amplifier (VISA) under the control of a cancer-specific promoter both in vitro and in vivo. C-VISA-BikDD e...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Transl Res
Egile Nagusiak: Sun, Ye, Ponz-Sarvise, Mariano, Chang, Shih-Shin, Chang, Wei-Chao, Chen, Chung-Hsuan, Hsu, Jennifer L, Hung, Mien-Chie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399095/
https://ncbi.nlm.nih.gov/pubmed/25901200
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