The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation

Both clinical and experimental evidence have firmly established that chronic pancreatitis, in particular in the context of Kras oncogenic mutations, predisposes to pancreatic ductal adenocarcinoma (PDAC). However, the repertoire of molecular mediators of pancreatitis involved in Kras-mediated initia...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Loncle, C, Molejon, M I, Lac, S, Tellechea, J I, Lomberk, G, Gramatica, L, Fernandez Zapico, M F, Dusetti, N, Urrutia, R, Iovanna, J L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973346/
https://ncbi.nlm.nih.gov/pubmed/27415425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.202
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