The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation

Both clinical and experimental evidence have firmly established that chronic pancreatitis, in particular in the context of Kras oncogenic mutations, predisposes to pancreatic ductal adenocarcinoma (PDAC). However, the repertoire of molecular mediators of pancreatitis involved in Kras-mediated initia...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Loncle, C, Molejon, M I, Lac, S, Tellechea, J I, Lomberk, G, Gramatica, L, Fernandez Zapico, M F, Dusetti, N, Urrutia, R, Iovanna, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973346/
https://ncbi.nlm.nih.gov/pubmed/27415425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.202
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