Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration

Necroptosis is a programmed, caspase-independent cell death that is morphologically similar to necrosis. TNF-induced necroptosis is mediated by receptor-interacting protein kinases, RIP1 and RIP3, and the mixed lineage kinase domain-like (MLKL). After being phosphorylated by RIP3, MLKL is translocat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Res
Egile Nagusiak: Cai, Zhenyu, Zhang, Anling, Choksi, Swati, Li, Weihua, Li, Tao, Zhang, Xue-Min, Liu, Zheng-Gang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973336/
https://ncbi.nlm.nih.gov/pubmed/27444869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.87
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