Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration

Necroptosis is a programmed, caspase-independent cell death that is morphologically similar to necrosis. TNF-induced necroptosis is mediated by receptor-interacting protein kinases, RIP1 and RIP3, and the mixed lineage kinase domain-like (MLKL). After being phosphorylated by RIP3, MLKL is translocat...

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Dades bibliogràfiques
Publicat a:Cell Res
Autors principals: Cai, Zhenyu, Zhang, Anling, Choksi, Swati, Li, Weihua, Li, Tao, Zhang, Xue-Min, Liu, Zheng-Gang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973336/
https://ncbi.nlm.nih.gov/pubmed/27444869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.87
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