Role of Retinoic Acid Receptor-γ in DNA Damage-Induced Necroptosis

DNA-damaging compounds, commonly used as chemotherapeutic drugs, are known to trigger cells to undergo programmed cell death such as apoptosis and necroptosis. However, the molecular mechanism of DNA damage-induced cell death is not fully understood. Here, we report that RARγ has a critical role in...

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Publicat a:iScience
Autors principals: Kadigamuwa, Chamila, Choksi, Swati, Xu, Qing, Cataisson, Christophe, Greenbaum, Steven S., Yuspa, Stuart H., Liu, Zheng-gang
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606929/
https://ncbi.nlm.nih.gov/pubmed/31255985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.06.019
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