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Sur8 mediates tumorigenesis and metastasis in colorectal cancer
Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is inc...
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| Gepubliceerd in: | Exp Mol Med |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973316/ https://ncbi.nlm.nih.gov/pubmed/27469030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.58 |
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