A carregar...
Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
High-frequency point mutations of genes encoding histones have been identified recently as novel drivers in a number of tumors. Specifically, the H3K36M/I mutations were shown to be oncogenic in chondroblastomas and undifferentiated sarcomas by inhibiting H3K36 methyltransferases, including SETD2. H...
Na minha lista:
| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973290/ https://ncbi.nlm.nih.gov/pubmed/27474439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.284323.116 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|