Загрузка...
Ligand-induced Ordering of the C-terminal Tail Primes STING for Phosphorylation by TBK1
The innate immune protein Stimulator of interferon genes (STING) promotes the induction of interferon beta (IFN-β) production via the phosphorylation of its C-terminal tail (CTT) by TANK-binding kinase 1 (TBK1). Potent ligands of STING are, therefore, promising candidates for novel anti-cancer drugs...
Сохранить в:
| Опубликовано в: : | EBioMedicine |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2016
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972534/ https://ncbi.nlm.nih.gov/pubmed/27333035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.05.039 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|