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Synergistically acting agonists and antagonists of G protein–coupled receptors prevent photoreceptor cell degeneration

Photoreceptor cell degeneration leads to visual impairment and blindness in several types of retinal disease. However, the discovery of safe and effective therapeutic strategies conferring photoreceptor cell protection remains challenging. Targeting distinct cellular pathways with low doses of diffe...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Chen, Yu, Palczewska, Grazyna, Masuho, Ikuo, Gao, Songqi, Jin, Hui, Dong, Zhiqian, Gieser, Linn, Brooks, Matthew J., Kiser, Philip D., Kern, Timothy S., Martemyanov, Kirill A., Swaroop, Anand, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972460/
https://ncbi.nlm.nih.gov/pubmed/27460988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag0245
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