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Synergistically acting agonists and antagonists of G protein–coupled receptors prevent photoreceptor cell degeneration

Photoreceptor cell degeneration leads to visual impairment and blindness in several types of retinal disease. However, the discovery of safe and effective therapeutic strategies conferring photoreceptor cell protection remains challenging. Targeting distinct cellular pathways with low doses of diffe...

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Dades bibliogràfiques
Publicat a:Sci Signal
Autors principals: Chen, Yu, Palczewska, Grazyna, Masuho, Ikuo, Gao, Songqi, Jin, Hui, Dong, Zhiqian, Gieser, Linn, Brooks, Matthew J., Kiser, Philip D., Kern, Timothy S., Martemyanov, Kirill A., Swaroop, Anand, Palczewski, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972460/
https://ncbi.nlm.nih.gov/pubmed/27460988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag0245
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