TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control T(H)2-Mediated Immunopathology

Persistent T(H)2 cytokine responses following chronic helminth infections can often lead to the development of tissue pathology and fibrotic scarring. Despite a good understanding of the cellular mechanisms involved in fibrogenesis, there are very few therapeutic options available, highlighting a si...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Kannan, Yashaswini, Perez-Lloret, Jimena, Li, Yanda, Entwistle, Lewis J., Khoury, Hania, Papoutsopoulou, Stamatia, Mahmood, Radma, Mansour, Nuha R., Ching-Cheng Huang, Stanley, Pearce, Edward J., Pedro S. de Carvalho, Luiz, Ley, Steven C., Wilson, Mark S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972396/
https://ncbi.nlm.nih.gov/pubmed/27487182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005783
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