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Primer Extension Reactions for the PCR- based α- complementation Assay

The PCR- based- α- complementation assay is an effective technique to measure the fidelity of polymerases, especially RNA-dependent RNA polymerases (RDRP) and Reverse Transcriptases (RT). It has been successfully employed to determine the fidelity of the poliovirus polymerase 3D-pol (DeStefano, 2010...

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Detalles Bibliográficos
Publicado en:Bio Protoc
Main Authors: Achuthan, Vasudevan, DeStefano, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972330/
https://ncbi.nlm.nih.gov/pubmed/27500187
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