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Molecular dynamic study of MlaC protein in Gram‐negative bacteria: conformational flexibility, solvent effect and protein‐phospholipid binding

The composition of the outer membrane in Gram‐negative bacteria is asymmetric, with the lipopolysaccharides found in the outer leaflet and phospholipids in the inner leaflet. The MlaC protein transfers phospholipids from the outer to inner membrane to maintain such lipid asymmetry in the Mla pathway...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Huang, Yu‐ming M., Miao, Yinglong, Munguia, Jason, Lin, Leo, Nizet, Victor, McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972199/
https://ncbi.nlm.nih.gov/pubmed/27111825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2939
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