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Docking simulation and antibiotic discovery targeting the MlaC protein in Gram-negative bacteria
To maintain the lipid asymmetry of the cell envelope in Gram-negative bacteria, the MlaC protein serves as a lipid-transfer factor and delivers phospholipids from the outer to the inner membrane. A strategy of antibiotic discovery is to design a proper compound that can tightly bind to the MlaC prot...
Shranjeno v:
| izdano v: | Chem Biol Drug Des |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737922/ https://ncbi.nlm.nih.gov/pubmed/30570806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13462 |
| Oznake: |
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