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Structural propensities of kinase family proteins from a Potts model of residue co‐variation

Understanding the conformational propensities of proteins is key to solving many problems in structural biology and biophysics. The co‐variation of pairs of mutations contained in multiple sequence alignments of protein families can be used to build a Potts Hamiltonian model of the sequence patterns...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Protein Sci
Prif Awduron: Haldane, Allan, Flynn, William F., He, Peng, Vijayan, R.S.K., Levy, Ronald M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972195/
https://ncbi.nlm.nih.gov/pubmed/27241634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2954
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