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Population pharmacokinetic analysis to recommend the optimal dose of udenafil in patients with mild and moderate hepatic impairment

AIMS: The aim of this study was to develop a population pharmacokinetic (PK) model of udenafil and its active metabolite, DA‐8164, in healthy subjects and patients with hepatic impairment (HI) and to estimate the optimal dosing recommendations for patients with HI. METHODS: An open label, three para...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Br J Clin Pharmacol
Päätekijät: Kim, Anhye, Lee, Jongtae, Shin, Donghoon, Jung, Yong Jin, Bahng, Mi Young, Cho, Joo‐Youn, Jang, In‐Jin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972155/
https://ncbi.nlm.nih.gov/pubmed/27084997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12977
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