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Population pharmacokinetic analysis to recommend the optimal dose of udenafil in patients with mild and moderate hepatic impairment

AIMS: The aim of this study was to develop a population pharmacokinetic (PK) model of udenafil and its active metabolite, DA‐8164, in healthy subjects and patients with hepatic impairment (HI) and to estimate the optimal dosing recommendations for patients with HI. METHODS: An open label, three para...

詳細記述

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書誌詳細
出版年:Br J Clin Pharmacol
主要な著者: Kim, Anhye, Lee, Jongtae, Shin, Donghoon, Jung, Yong Jin, Bahng, Mi Young, Cho, Joo‐Youn, Jang, In‐Jin
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972155/
https://ncbi.nlm.nih.gov/pubmed/27084997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12977
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