Pharmacokinetics and pharmacodynamics of liposomal mifamurtide in adult volunteers with mild or moderate renal impairment

AIMS: To evaluate the pharmacokinetics and pharmacodynamics following a single dose of liposomal mifamurtide (L-MTP-PE, MEPACT®) in adult subjects with mild (calculated creatinine clearance [CL(cr)] of 50–80 ml min(−1)) or moderate (CL(cr) 30–50 ml min(−1)) renal impairment in comparison with age-,...

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Detalhes bibliográficos
Main Authors: Venkatakrishnan, Karthik, Liu, Yi, Noe, Dennis, Mertz, Jaime, Bargfrede, Michael, Marbury, Thomas, Farbakhsh, Kambiz, Oliva, Cristina, Milton, Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093924/
https://ncbi.nlm.nih.gov/pubmed/24134181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12260
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