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Population pharmacokinetic analysis to recommend the optimal dose of udenafil in patients with mild and moderate hepatic impairment

AIMS: The aim of this study was to develop a population pharmacokinetic (PK) model of udenafil and its active metabolite, DA‐8164, in healthy subjects and patients with hepatic impairment (HI) and to estimate the optimal dosing recommendations for patients with HI. METHODS: An open label, three para...

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書目詳細資料
發表在:Br J Clin Pharmacol
Main Authors: Kim, Anhye, Lee, Jongtae, Shin, Donghoon, Jung, Yong Jin, Bahng, Mi Young, Cho, Joo‐Youn, Jang, In‐Jin
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972155/
https://ncbi.nlm.nih.gov/pubmed/27084997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12977
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