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Functional versus non-functional intratumor heterogeneity in cancer
Next-generation sequencing data from human cancers are often difficult to interpret within the context of tumor evolution. We developed a mathematical model describing the accumulation of mutations under neutral evolutionary dynamics and showed that 323/904 cancers (∼30%) from multiple types were co...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972105/ https://ncbi.nlm.nih.gov/pubmed/27652316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1162897 |
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