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Viral-mediated Ntf3 overexpression disrupts innervation and hearing in nondeafened guinea pig cochleae
Synaptopathy in the cochlea occurs when the connection between inner hair cells and the auditory nerve is disrupted, leading to impaired hearing and nerve degeneration. Experiments using transgenic mice have shown that overexpression of NT3 by supporting cells repairs synaptopathy caused by overstim...
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| Publicat a: | Mol Ther Methods Clin Dev |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972090/ https://ncbi.nlm.nih.gov/pubmed/27525291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.52 |
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