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Differential Effects of AAV.BDNF and AAV.Ntf3 in the Deafened Adult Guinea Pig Ear

Cochlear hair cell loss results in secondary regression of peripheral auditory fibers (PAFs) and loss of spiral ganglion neurons (SGNs). The performance of cochlear implants (CI) in rehabilitating hearing depends on survival of SGNs. Here we compare the effects of adeno-associated virus vectors with...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Budenz, Cameron L., Wong, Hiu Tung, Swiderski, Donald L., Shibata, Seiji B., Pfingst, Bryan E., Raphael, Yehoash
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649680/
https://ncbi.nlm.nih.gov/pubmed/25726967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08619
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