Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes That Promote Autophagic Tau Clearance

We previously discovered that one specific scalemic preparation of myricanol (1), a constituent of Myrica cerifera (bayberry/southern wax myrtle) root bark, could lower the levels of the microtubule-associated protein tau (MAPT). The significance is that tau accumulates in a number of neurodegenerat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Martin, Mackenzie D., Calcul, Laurent, Smith, Courtney, Jinwal, Umesh K., Fontaine, Sarah N., Darling, April, Seeley, Kent, Wojtas, Lukasz, Narayan, Malathi, Gestwicki, Jason E., Smith, Garry R., Reitz, Allen B., Baker, Bill J., Dickey, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971885/
https://ncbi.nlm.nih.gov/pubmed/25588114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb501013w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados