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Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model

Astrocytes are key participants in various aspects of brain development and function, many of which are executed via secreted proteins. Defects in astrocyte signaling are implicated in neurodevelopmental disorders characterized by abnormal neural circuitry such as Fragile X syndrome (FXS). In animal...

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Bibliografski detalji
Izdano u:Mol Brain
Glavni autori: Cheng, Connie, Lau, Sally K. M., Doering, Laurie C.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971702/
https://ncbi.nlm.nih.gov/pubmed/27485117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0256-9
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