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Regulation of IL-6 Secretion by Astrocytes via TLR4 in the Fragile X Mouse Model

Fragile X syndrome (FXS) is identified by abnormal dendrite morphology and altered synaptic protein expression. Astrocyte secreted factors such as Tenascin C (TNC), may contribute to the synaptic changes, including maturation of the synapse. TNC is a known endogenous ligand of toll-like receptor 4 (...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Krasovska, Victoria, Doering, Laurie C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085486/
https://ncbi.nlm.nih.gov/pubmed/30123107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00272
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