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Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model

Astrocytes are key participants in various aspects of brain development and function, many of which are executed via secreted proteins. Defects in astrocyte signaling are implicated in neurodevelopmental disorders characterized by abnormal neural circuitry such as Fragile X syndrome (FXS). In animal...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Cheng, Connie, Lau, Sally K. M., Doering, Laurie C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971702/
https://ncbi.nlm.nih.gov/pubmed/27485117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0256-9
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