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Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model

Astrocytes are key participants in various aspects of brain development and function, many of which are executed via secreted proteins. Defects in astrocyte signaling are implicated in neurodevelopmental disorders characterized by abnormal neural circuitry such as Fragile X syndrome (FXS). In animal...

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Vydáno v:Mol Brain
Hlavní autoři: Cheng, Connie, Lau, Sally K. M., Doering, Laurie C.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971702/
https://ncbi.nlm.nih.gov/pubmed/27485117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0256-9
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