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Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic Residues

Commensal and pathogenic enteric bacteria have developed several systems to adapt to proton leakage into the cytoplasm resulting from extreme acidic conditions. One such system involves arginine uptake followed by export of the decarboxylated product agmatine, carried out by the arginine/agmatine an...

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Publicado en:PLoS One
Autores principales: Krammer, Eva-Maria, Ghaddar, Kassem, André, Bruno, Prévost, Martine
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970712/
https://ncbi.nlm.nih.gov/pubmed/27482712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160219
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