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Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic Residues

Commensal and pathogenic enteric bacteria have developed several systems to adapt to proton leakage into the cytoplasm resulting from extreme acidic conditions. One such system involves arginine uptake followed by export of the decarboxylated product agmatine, carried out by the arginine/agmatine an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Krammer, Eva-Maria, Ghaddar, Kassem, André, Bruno, Prévost, Martine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970712/
https://ncbi.nlm.nih.gov/pubmed/27482712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160219
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