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Molecular mechanism of substrate selectivity of the arginine-agmatine Antiporter AdiC

The arginine-agmatine antiporter (AdiC) is a component of an acid resistance system developed by enteric bacteria to resist gastric acidity. In order to avoid neutral proton antiport, the monovalent form of arginine, about as abundant as its divalent form under acidic conditions, should be selective...

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Pubblicato in:Sci Rep
Autori principali: Krammer, Eva-Maria, Gibbons, Andrew, Roos, Goedele, Prévost, Martine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199258/
https://ncbi.nlm.nih.gov/pubmed/30353119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33963-1
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