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Molecular mechanism of pH-dependent substrate transport by an arginine-agmatine antiporter

Enteropathogenic bacteria, exemplified by Escherichia coli, rely on acid-resistance systems (ARs) to survive the acidic environment of the stomach. AR3 consumes intracellular protons through decarboxylation of arginine (Arg) in the cytoplasm and exchange of the reaction product agmatine (Agm) with e...

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Detalhes bibliográficos
Main Authors: Wang, Sheng, Yan, Renhong, Zhang, Xi, Chu, Qi, Shi, Yigong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156701/
https://ncbi.nlm.nih.gov/pubmed/25136114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414093111
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