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Molecular mechanism of pH-dependent substrate transport by an arginine-agmatine antiporter

Enteropathogenic bacteria, exemplified by Escherichia coli, rely on acid-resistance systems (ARs) to survive the acidic environment of the stomach. AR3 consumes intracellular protons through decarboxylation of arginine (Arg) in the cytoplasm and exchange of the reaction product agmatine (Agm) with e...

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Bibliografiske detaljer
Main Authors: Wang, Sheng, Yan, Renhong, Zhang, Xi, Chu, Qi, Shi, Yigong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156701/
https://ncbi.nlm.nih.gov/pubmed/25136114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414093111
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