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Molecular mechanism of pH-dependent substrate transport by an arginine-agmatine antiporter

Enteropathogenic bacteria, exemplified by Escherichia coli, rely on acid-resistance systems (ARs) to survive the acidic environment of the stomach. AR3 consumes intracellular protons through decarboxylation of arginine (Arg) in the cytoplasm and exchange of the reaction product agmatine (Agm) with e...

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Autori principali: Wang, Sheng, Yan, Renhong, Zhang, Xi, Chu, Qi, Shi, Yigong
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156701/
https://ncbi.nlm.nih.gov/pubmed/25136114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414093111
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