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Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status

Sirtuins (SIRT) belonging to the NAD+ dependent histone deacetylase III class of enzymes have emerged as master regulators of metabolism and longevity. However, their role in prevention of organismal aging and cellular senescence still remains controversial. In the present study, we now report upreg...

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Vydáno v:Cell Cycle
Hlavní autoři: Anwar, Tarique, Khosla, Sanjeev, Ramakrishna, Gayatri
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968900/
https://ncbi.nlm.nih.gov/pubmed/27229617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1189041
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