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DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression

DNA damage tolerance facilitates the progression of replication forks that have encountered obstacles on the template strands. It involves either translesion DNA synthesis initiated by proliferating cell nuclear antigen monoubiquitination or less well-characterized fork reversal and template switch...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hampp, Stephanie, Kiessling, Tina, Buechle, Kerstin, Mansilla, Sabrina F., Thomale, Jürgen, Rall, Melanie, Ahn, Jinwoo, Pospiech, Helmut, Gottifredi, Vanesa, Wiesmüller, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968756/
https://ncbi.nlm.nih.gov/pubmed/27407148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605828113
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