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Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability
Faithful genome duplication and inheritance require the complete resolution of all intertwines within the parental DNA duplex. This is achieved by topoisomerase action ahead of the replication fork or by fork rotation and subsequent resolution of the DNA precatenation formed. Although fork rotation...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547287/ https://ncbi.nlm.nih.gov/pubmed/26240319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505356112 |
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