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The Tip of an Iceberg: Replication-Associated Functions of the Tumor Suppressor p53
The tumor suppressor p53 is a transcriptional factor broadly mutated in cancer. Most inactivating and gain of function mutations disrupt the sequence-specific DNA binding domain, which activates target genes. This is perhaps the main reason why most research has focused on the relevance of such tran...
Gorde:
| Argitaratua izan da: | Cancers (Basel) |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
MDPI
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6115784/ https://ncbi.nlm.nih.gov/pubmed/30060597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10080250 |
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