Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations

BACKGROUND: Non-celiac wheat sensitivity is an emerging wheat-related syndrome showing peak prevalence in Western populations. Recent studies hypothesize that new gliadin alleles introduced in the human diet by replacement of ancient wheat with modern varieties can prompt immune responses mediated b...

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Detalhes bibliográficos
Publicado no:Genes Nutr
Principais autores: Sazzini, Marco, De Fanti, Sara, Cherubini, Anna, Quagliariello, Andrea, Profiti, Giuseppe, Martelli, Pier Luigi, Casadio, Rita, Ricci, Chiara, Campieri, Massimo, Lanzini, Alberto, Volta, Umberto, Caio, Giacomo, Franceschi, Claudio, Spisni, Enzo, Luiselli, Donata
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968434/
https://ncbi.nlm.nih.gov/pubmed/27551316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-016-0532-4
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