SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

Proper regulation of mitophagy for mitochondrial homeostasis is important in various inflammatory diseases. However, the precise mechanisms by which mitophagy is activated to regulate inflammatory responses remain largely unknown. The NLRP3 (NLR family, pyrin domain containing 3) inflammasome serves...

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Dades bibliogràfiques
Publicat a:Autophagy
Autors principals: Kim, Min-Ji, Bae, Soo Han, Ryu, Jae-Chan, Kwon, Younghee, Oh, Ji-Hwan, Kwon, Jeongho, Moon, Jong-Seok, Kim, Kyubo, Miyawaki, Atsushi, Lee, Min Goo, Shin, Jaekyoon, Kim, Young Sam, Kim, Chang-Hoon, Ryter, Stefan W., Choi, Augustine M. K., Rhee, Sue Goo, Ryu, Ji-Hwan, Yoon, Joo-Heon
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Basic Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968237/
https://ncbi.nlm.nih.gov/pubmed/27337507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1183081
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