SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

Proper regulation of mitophagy for mitochondrial homeostasis is important in various inflammatory diseases. However, the precise mechanisms by which mitophagy is activated to regulate inflammatory responses remain largely unknown. The NLRP3 (NLR family, pyrin domain containing 3) inflammasome serves...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Kim, Min-Ji, Bae, Soo Han, Ryu, Jae-Chan, Kwon, Younghee, Oh, Ji-Hwan, Kwon, Jeongho, Moon, Jong-Seok, Kim, Kyubo, Miyawaki, Atsushi, Lee, Min Goo, Shin, Jaekyoon, Kim, Young Sam, Kim, Chang-Hoon, Ryter, Stefan W., Choi, Augustine M. K., Rhee, Sue Goo, Ryu, Ji-Hwan, Yoon, Joo-Heon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Basic Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968237/
https://ncbi.nlm.nih.gov/pubmed/27337507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1183081
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