SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

Proper regulation of mitophagy for mitochondrial homeostasis is important in various inflammatory diseases. However, the precise mechanisms by which mitophagy is activated to regulate inflammatory responses remain largely unknown. The NLRP3 (NLR family, pyrin domain containing 3) inflammasome serves...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Kim, Min-Ji, Bae, Soo Han, Ryu, Jae-Chan, Kwon, Younghee, Oh, Ji-Hwan, Kwon, Jeongho, Moon, Jong-Seok, Kim, Kyubo, Miyawaki, Atsushi, Lee, Min Goo, Shin, Jaekyoon, Kim, Young Sam, Kim, Chang-Hoon, Ryter, Stefan W., Choi, Augustine M. K., Rhee, Sue Goo, Ryu, Ji-Hwan, Yoon, Joo-Heon
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968237/
https://ncbi.nlm.nih.gov/pubmed/27337507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1183081
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