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Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms

RING‐in‐between‐RING (RBR) ubiquitin (Ub) ligases are a distinct class of E3s, defined by a RING1 domain that binds E2 Ub‐conjugating enzyme and a RING2 domain that contains an active site cysteine similar to HECT‐type E3s. Proposed to function as RING/HECT hybrids, details regarding the Ub transfer...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Dove, Katja K, Stieglitz, Benjamin, Duncan, Emily D, Rittinger, Katrin, Klevit, Rachel E
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967960/
https://ncbi.nlm.nih.gov/pubmed/27312108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642641
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