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Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases
RING-between-RING (RBR) ubiquitin ligases work with multiple E2 enzymes and function through an E3-ubiquitin thioester intermediate. The RBR module comprises three domains, RING1, IBR and RING2 that collaborate to transfer ubiquitin from the E2~Ub conjugate, recognised by RING1, onto a catalytic cys...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758712/ https://ncbi.nlm.nih.gov/pubmed/29311602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18513-5 |
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